Autoluminescent Mycobacterium tuberculosis for Rapid, Real-Time, Non-Invasive Assessment of Drug and Vaccine Efficacy

Preclinical efforts to discover and develop new drugs and vaccines for tuberculosis are hampered by the reliance on colony-forming unit (CFU) counts as primary outcomes for in vivo efficacy studies and the slow growth of Mycobacterium tuberculosis. The utility of bioluminescent M. tuberculosis repor...

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Detalles Bibliográficos
Autores principales: Zhang, Tianyu, Li, Si-Yang, Nuermberger, Eric L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256174/
https://www.ncbi.nlm.nih.gov/pubmed/22253776
http://dx.doi.org/10.1371/journal.pone.0029774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256174/
https://www.ncbi.nlm.nih.gov/pubmed/22253776
http://dx.doi.org/10.1371/journal.pone.0029774

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