Postnatal Changes in the Expression Pattern of the Imprinted Signalling Protein XLαs Underlie the Changing Phenotype of Deficient Mice

The alternatively spliced trimeric G-protein subunit XLαs, which is involved in cAMP signalling, is encoded by the Gnasxl transcript of the imprinted Gnas locus. XLαs deficient mice show neonatal feeding problems, leanness, inertia and a high mortality rate. Mutants that survive to weaning age devel...

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Detalles Bibliográficos
Autores principales: Krechowec, Stefan O., Burton, Katie L., Newlaczyl, Anna U., Nunn, Nicolas, Vlatković, Nikolina, Plagge, Antonius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256176/
https://www.ncbi.nlm.nih.gov/pubmed/22253771
http://dx.doi.org/10.1371/journal.pone.0029753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256176/
https://www.ncbi.nlm.nih.gov/pubmed/22253771
http://dx.doi.org/10.1371/journal.pone.0029753

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