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BRCAness Profile of Sporadic Ovarian Cancer Predicts Disease Recurrence

BACKGROUND: The consequences of defective homologous recombination (HR) are not understood in sporadic ovarian cancer, nor have the potential role of HR proteins other than BRCA1 and BRCA2 been clearly defined. However, it is clear that defects in HR and other DNA repair pathways are important to th...

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Detalles Bibliográficos
Autores principales: Wysham, Weiya Z., Mhawech-Fauceglia, Paulette, Li, Hong, Hays, Laura, Syriac, Suzanna, Skrepnik, Tijana, Wright, Jay, Pande, Nupur, Hoatlin, Maureen, Pejovic, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256213/
https://www.ncbi.nlm.nih.gov/pubmed/22253870
http://dx.doi.org/10.1371/journal.pone.0030042