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Resistance of MLL–AFF1-positive acute lymphoblastic leukemia to tumor necrosis factor-alpha is mediated by S100A6 upregulation

Mixed-lineage leukemia (MLL)–AFF1 (MLL–AF4)-positive acute lymphoblastic leukemia (ALL) is associated with poor prognosis, even after allogeneic hematopoietic stem cell transplantation (allo-HSCT). The resistance to graft-versus-leukemia (GVL) effects may be responsible for the poor effect of allo-H...

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Detalles Bibliográficos
Autores principales: Tamai, H, Miyake, K, Yamaguchi, H, Takatori, M, Dan, K, Inokuchi, K, Shimada, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256756/
https://www.ncbi.nlm.nih.gov/pubmed/22829076
http://dx.doi.org/10.1038/bcj.2011.37