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Clostridium difficile Cell Wall Protein CwpV Undergoes Enzyme-independent Intramolecular Autoproteolysis

Clostridium difficile infection is a leading cause of antibiotic-associated diarrhea, placing considerable economic pressure on healthcare systems and resulting in significant morbidity and mortality. The pathogen produces a proteinaceous array on its cell surface known as the S-layer, consisting pr...

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Detalles Bibliográficos
Autores principales: Dembek, Marcin, Reynolds, Catherine B., Fairweather, Neil F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256870/
https://www.ncbi.nlm.nih.gov/pubmed/22128177
http://dx.doi.org/10.1074/jbc.M111.302463