A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

The T cell receptor (TCR) orchestrates immune responses by binding to foreign peptides presented at the cell surface in the context of major histocompatibility complex (MHC) molecules. Effective immunity requires that all possible foreign peptide-MHC molecules are recognized or risks leaving holes i...

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Detalles Bibliográficos
Autores principales: Wooldridge, Linda, Ekeruche-Makinde, Julia, van den Berg, Hugo A., Skowera, Anna, Miles, John J., Tan, Mai Ping, Dolton, Garry, Clement, Mathew, Llewellyn-Lacey, Sian, Price, David A., Peakman, Mark, Sewell, Andrew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256900/
https://www.ncbi.nlm.nih.gov/pubmed/22102287
http://dx.doi.org/10.1074/jbc.M111.289488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256900/
https://www.ncbi.nlm.nih.gov/pubmed/22102287
http://dx.doi.org/10.1074/jbc.M111.289488

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