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An Electrostatic Switch Controls Palmitoylation of the Large Conductance Voltage- and Calcium-activated Potassium (BK) Channel

Protein palmitoylation is a major dynamic posttranslational regulator of protein function. However, mechanisms that control palmitoylation are poorly understood. In many proteins, palmitoylation occurs at cysteine residues juxtaposed to membrane-anchoring domains such as transmembrane helices, sites...

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Detalles Bibliográficos
Autores principales: Jeffries, Owen, Tian, Lijun, McClafferty, Heather, Shipston, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256903/
https://www.ncbi.nlm.nih.gov/pubmed/22084244
http://dx.doi.org/10.1074/jbc.M111.224840