Identification of Simple Compounds with Microtubule-Binding Activity That Inhibit Cancer Cell Growth with High Potency

[Image: see text] We analyzed more than 1 million small molecules with the goal of finding simple synthetic compounds that potently inhibit cancer cell growth. We identified three such compounds with unknown mechanisms of action. Subsequent studies revealed that all three of these small molecules ta...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Wan Seok, Shimada, Kenichi, Delva, Darnelle, Patel, Milesh, Ode, Egberamwen, Skouta, Rachid, Stockwell, Brent R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256933/
https://www.ncbi.nlm.nih.gov/pubmed/22247791
http://dx.doi.org/10.1021/ml200195s

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256933/
https://www.ncbi.nlm.nih.gov/pubmed/22247791
http://dx.doi.org/10.1021/ml200195s

Ejemplares similares