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Chemokines control naive CD8(+) T cell selection of optimal lymph node antigen presenting cells

Naive antiviral CD8(+) T cells are activated in the draining LN (DLN) by dendritic cells (DCs) presenting viral antigens. However, many viruses infect LN macrophages, which participate in initiation of innate immunity and B cell activation. To better understand how and why T cells select infected DC...

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Detalles Bibliográficos
Autores principales: Hickman, Heather D., Li, Lily, Reynoso, Glennys V., Rubin, Erica J., Skon, Cara N., Mays, Jacqueline W., Gibbs, James, Schwartz, Owen, Bennink, Jack R., Yewdell, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256957/
https://www.ncbi.nlm.nih.gov/pubmed/22042976
http://dx.doi.org/10.1084/jem.20102545