MHC class I–specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice

Transfusion-related acute lung injury (TRALI), a form of noncardiogenic pulmonary edema that develops during or within 6 h after a blood transfusion, is the most frequent cause of transfusion-associated death in the United States. Because development of TRALI is associated with donor antibodies (Abs...

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Detalles Bibliográficos
Autores principales: Strait, Richard T., Hicks, Wyenona, Barasa, Nathaniel, Mahler, Ashley, Khodoun, Marat, Köhl, Jörg, Stringer, Keith, Witte, David, Van Rooijen, Nico, Susskind, Brian M., Finkelman, Fred D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256958/
https://www.ncbi.nlm.nih.gov/pubmed/22025304
http://dx.doi.org/10.1084/jem.20110159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256958/
https://www.ncbi.nlm.nih.gov/pubmed/22025304
http://dx.doi.org/10.1084/jem.20110159

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