Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity

Ecotropic viral integration site 1 (Evi1), a transcription factor of the SET/PR domain protein family, is essential for the maintenance of hematopoietic stem cells (HSCs) in mice and is overexpressed in several myeloid malignancies. Here, we generate reporter mice in which an internal ribosome entry...

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Detalles Bibliográficos
Autores principales: Kataoka, Keisuke, Sato, Tomohiko, Yoshimi, Akihide, Goyama, Susumu, Tsuruta, Takako, Kobayashi, Hiroshi, Shimabe, Munetake, Arai, Shunya, Nakagawa, Masahiro, Imai, Yoichi, Kumano, Keiki, Kumagai, Katsuyoshi, Kubota, Naoto, Kadowaki, Takashi, Kurokawa, Mineo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256960/
https://www.ncbi.nlm.nih.gov/pubmed/22084405
http://dx.doi.org/10.1084/jem.20110447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256960/
https://www.ncbi.nlm.nih.gov/pubmed/22084405
http://dx.doi.org/10.1084/jem.20110447

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