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Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo

Plasmacytoid dendritic cells (pDCs) specialize in the secretion of type I interferons (IFN-I) and thus are considered critical mediators of antiviral responses. We recently reported that pDCs have a very early but limited and transient capacity to curtail viral infections. Additionally, pDC numbers...

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Detalles Bibliográficos
Autores principales: Swiecki, Melissa, Wang, Yaming, Vermi, William, Gilfillan, Susan, Schreiber, Robert D., Colonna, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256963/
https://www.ncbi.nlm.nih.gov/pubmed/22084408
http://dx.doi.org/10.1084/jem.20110654