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REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase

Activation-induced deaminase (AID) acts on the immunoglobulin loci in activated B lymphocytes to initiate antibody gene diversification. The abundance of AID in the nucleus appears tightly regulated, with most nuclear AID being either degraded or exported back to the cytoplasm. To gain insight into...

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Detalles Bibliográficos
Autores principales: Uchimura, Yasuhiro, Barton, Lance F., Rada, Cristina, Neuberger, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256965/
https://www.ncbi.nlm.nih.gov/pubmed/22042974
http://dx.doi.org/10.1084/jem.20110856