Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

Adjuvants are critical for the success of vaccines. Agonists of microbial pattern recognition receptors (PRRs) are promising new adjuvant candidates. A mechanism through which adjuvants enhance immune responses is to stimulate innate immunity. We studied the innate immune response in humans to synth...

Descripción completa

Detalles Bibliográficos
Autores principales: Caskey, Marina, Lefebvre, François, Filali-Mouhim, Abdelali, Cameron, Mark J., Goulet, Jean-Philippe, Haddad, Elias K., Breton, Gaëlle, Trumpfheller, Christine, Pollak, Sarah, Shimeliovich, Irina, Duque-Alarcon, Angela, Pan, Li, Nelkenbaum, Annette, Salazar, Andres M., Schlesinger, Sarah J., Steinman, Ralph M., Sékaly, Rafick P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256967/
https://www.ncbi.nlm.nih.gov/pubmed/22065672
http://dx.doi.org/10.1084/jem.20111171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256967/
https://www.ncbi.nlm.nih.gov/pubmed/22065672
http://dx.doi.org/10.1084/jem.20111171

Ejemplares similares