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Losartan modulates muscular capillary density and reverses thiazide diuretic-exacerbated insulin resistance in fructose-fed rats

The renin–angiotensin system (RAS) is involved in the pathogenesis of insulin sensitivity (IS). The role of RAS in insulin resistance and muscular circulation has yet to be elucidated. Therefore, this study sought to determine the mechanisms of angiotensin II receptor blockers (ARBs) and/or diuretic...

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Detalles Bibliográficos
Autores principales: Guo, Qi, Mori, Takefumi, Jiang, Yue, Hu, Chunyan, Ohsaki, Yusuke, Yoneki, Yoshimi, Nakamichi, Takashi, Ogawa, Susumu, Sato, Hiroshi, Ito, Sadayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257041/
https://www.ncbi.nlm.nih.gov/pubmed/21900942
http://dx.doi.org/10.1038/hr.2011.140