Acute pyelonephritis and renal scarring are caused by dysfunctional innate immunity in mCxcr2 heterozygous mice

The CXCR1 receptor and chemokine CXCL8 (IL-8) support neutrophil-dependent clearance of uropathogenic Escherichia coli from the urinary tract. CXCR1 is reduced in children prone to pyelonephritis, and heterozygous hCXCR1 polymorphisms are more common in this patient group than in healthy individuals...

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Detalles Bibliográficos
Autores principales: Svensson, Majlis, Yadav, Manisha, Holmqvist, Bo, Lutay, Nataliya, Svanborg, Catharina, Godaly, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257042/
https://www.ncbi.nlm.nih.gov/pubmed/21814172
http://dx.doi.org/10.1038/ki.2011.257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257042/
https://www.ncbi.nlm.nih.gov/pubmed/21814172
http://dx.doi.org/10.1038/ki.2011.257

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