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Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II–mediated podocyte apoptosis

Podocytes have a significant role in establishing selective permeability of the glomerular filtration barrier. Sustained renin–angiotensin–aldosterone system activation is crucial to the pathogenesis of podocyte injury, but the mechanisms by which angiotensin II modulates podocyte survival due to ph...

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Detalles Bibliográficos
Autores principales: Hsu, Hsiang-Hao, Hoffmann, Sigrid, Di Marco, Giovana S, Endlich, Nicole, Peter-Katalinić, Jasna, Weide, Thomas, Pavenstädt, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257043/
https://www.ncbi.nlm.nih.gov/pubmed/21814176
http://dx.doi.org/10.1038/ki.2011.250