Cargando…

CD4(+) T cells from MHC II-dependent thymocyte–thymocyte interaction provide efficient help for B cells

Recently, a novel CD4(+) T-cell developmental pathway was reported that generates thymocyte–thymocyte (T–T) CD4(+) T cells. We established a mouse system (CIITA(tg)CIITApIV(−/−)) where thymic positive selection occurred only by major histocompatibility complex (MHC) class II(+) thymocytes. T–T CD4(+...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eun Ji, Choi, Bomi, Moon, Hana, Lee, You Jeong, Jeon, Yoon Kyeong, Park, Seong Hoe, Kim, Tae Jin, Jung, Kyeong Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257047/
https://www.ncbi.nlm.nih.gov/pubmed/21358747
http://dx.doi.org/10.1038/icb.2011.8