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CD4(+) T cells from MHC II-dependent thymocyte–thymocyte interaction provide efficient help for B cells
Recently, a novel CD4(+) T-cell developmental pathway was reported that generates thymocyte–thymocyte (T–T) CD4(+) T cells. We established a mouse system (CIITA(tg)CIITApIV(−/−)) where thymic positive selection occurred only by major histocompatibility complex (MHC) class II(+) thymocytes. T–T CD4(+...
Autores principales: | Kim, Eun Ji, Choi, Bomi, Moon, Hana, Lee, You Jeong, Jeon, Yoon Kyeong, Park, Seong Hoe, Kim, Tae Jin, Jung, Kyeong Cheon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257047/ https://www.ncbi.nlm.nih.gov/pubmed/21358747 http://dx.doi.org/10.1038/icb.2011.8 |
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