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Inhibition of Extracellular Signal-Regulated Kinases Ameliorates Hypertension-Induced Renal Vascular Remodeling in Rat Models

The aim of this study is to investigate the effect of the extracellular signal-regulated kinases 1/2 (ERK1/2) inhibitor, PD98059, on high blood pressure and related vascular changes. Blood pressure was recorded, thicknesses of renal small artery walls were measured and ERK1/2 immunoreactivity and er...

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Detalles Bibliográficos
Autores principales: Jing, Li, Zhang, Jianzhong, Sun, Jinping, Guo, Fengying, An, Xin, Yang, Kan, Li, Ping Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257072/
https://www.ncbi.nlm.nih.gov/pubmed/22272075
http://dx.doi.org/10.3390/ijms12128333