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Biochip-Based Detection of KRAS Mutation in Non-Small Cell Lung Cancer

This study is aimed at evaluating the potential of a biochip assay to sensitively detect KRAS mutation in DNA from non-small cell lung cancer (NSCLC) tissue samples. The assay covers 10 mutations in codons 12 and 13 of the KRAS gene, and is based on mutant-enriched PCR followed by reverse-hybridizat...

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Detalles Bibliográficos
Autores principales: Kriegshäuser, Gernot, Fabjani, Gerhild, Ziegler, Barbara, Zöchbauer-Müller, Sabine, End, Adelheid, Zeillinger, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257086/
https://www.ncbi.nlm.nih.gov/pubmed/22272089
http://dx.doi.org/10.3390/ijms12128530