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The Role of the E2F Transcription Factor Family in UV-Induced Apoptosis

The E2F transcription factor family is traditionally associated with cell cycle control. However, recent data has shown that activating E2Fs (E2F1-3a) are potent activators of apoptosis. In contrast, the recently cloned inhibitory E2Fs (E2F7 and 8) appear to antagonize E2F-induced cell death. In thi...

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Detalles Bibliográficos
Autores principales: Hazar-Rethinam, Mehlika, Endo-Munoz, Liliana, Gannon, Orla, Saunders, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257110/
https://www.ncbi.nlm.nih.gov/pubmed/22272113
http://dx.doi.org/10.3390/ijms12128947