3D QSAR Pharmacophore Modeling, in Silico Screening, and Density Functional Theory (DFT) Approaches for Identification of Human Chymase Inhibitors

Human chymase is a very important target for the treatment of cardiovascular diseases. Using a series of theoretical methods like pharmacophore modeling, database screening, molecular docking and Density Functional Theory (DFT) calculations, an investigation for identification of novel chymase inhib...

Descripción completa

Detalles Bibliográficos
Autores principales: Arooj, Mahreen, Thangapandian, Sundarapandian, John, Shalini, Hwang, Swan, Park, Jong Keun, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257128/
https://www.ncbi.nlm.nih.gov/pubmed/22272131
http://dx.doi.org/10.3390/ijms12129236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257128/
https://www.ncbi.nlm.nih.gov/pubmed/22272131
http://dx.doi.org/10.3390/ijms12129236

Ejemplares similares