QSAR Study and Molecular Design of Open-Chain Enaminones as Anticonvulsant Agents

Present work employs the QSAR formalism to predict the ED(50) anticonvulsant activity of ringed-enaminones, in order to apply these relationships for the prediction of unknown open-chain compounds containing the same types of functional groups in their molecular structure. Two different modeling app...

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Detalles Bibliográficos
Autores principales: Garro Martinez, Juan C., Duchowicz, Pablo R., Estrada, Mario R., Zamarbide, Graciela N., Castro, Eduardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257134/
https://www.ncbi.nlm.nih.gov/pubmed/22272137
http://dx.doi.org/10.3390/ijms12129354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257134/
https://www.ncbi.nlm.nih.gov/pubmed/22272137
http://dx.doi.org/10.3390/ijms12129354

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