Mutation of Rubie, a Novel Long Non-Coding RNA Located Upstream of Bmp4, Causes Vestibular Malformation in Mice

BACKGROUND: The vestibular apparatus of the vertebrate inner ear uses three fluid-filled semicircular canals to sense angular acceleration of the head. Malformation of these canals disrupts the sense of balance and frequently causes circling behavior in mice. The Epistatic circler (Ecl) is a complex...

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Detalles Bibliográficos
Autores principales: Roberts, Kristina A., Abraira, Victoria E., Tucker, Andrew F., Goodrich, Lisa V., Andrews, Nancy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257225/
https://www.ncbi.nlm.nih.gov/pubmed/22253730
http://dx.doi.org/10.1371/journal.pone.0029495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257225/
https://www.ncbi.nlm.nih.gov/pubmed/22253730
http://dx.doi.org/10.1371/journal.pone.0029495

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