Cargando…

Critical Roles of the WASP N-Terminal Domain and Btk in LPS-Induced Inflammatory Response in Macrophages

While Wiskott-Aldrich syndrome protein (WASP) plays critical roles in TCR signaling as an adaptor molecule, how it transduces innate immune signals remains to be elucidated. To investigate the roles of WASP in innate immune cells, we established bone marrow-derived macrophage (BMDM) cell lines from...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakuma, Chisato, Sato, Mitsuru, Takenouchi, Takato, Chiba, Joe, Kitani, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257260/
https://www.ncbi.nlm.nih.gov/pubmed/22253930
http://dx.doi.org/10.1371/journal.pone.0030351