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Lysosome-Membrane Fusion Mediated Superoxide Production in Hyperglycaemia-Induced Endothelial Dysfunction

Lysosomal exocytosis and fusion to cellular membrane is critical in the oxidative stress formation of endothelium under apoptotic stimulus. We investigated the role therein of it in hyperglycaemia-induced endothelial dysfunction. The lysosome-membrane fusion was shown by the expression of lamp1, the...

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Detalles Bibliográficos
Autores principales: Bao, Jun-Xiang, Chang, Hui, Lv, Yong-Gang, Yu, Jin-Wen, Bai, Yun-Gang, Liu, Huan, Cai, Yue, Wang, Ling, Ma, Jin, Chang, Yao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257261/
https://www.ncbi.nlm.nih.gov/pubmed/22253932
http://dx.doi.org/10.1371/journal.pone.0030387