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Lysosome-Membrane Fusion Mediated Superoxide Production in Hyperglycaemia-Induced Endothelial Dysfunction
Lysosomal exocytosis and fusion to cellular membrane is critical in the oxidative stress formation of endothelium under apoptotic stimulus. We investigated the role therein of it in hyperglycaemia-induced endothelial dysfunction. The lysosome-membrane fusion was shown by the expression of lamp1, the...
Autores principales: | Bao, Jun-Xiang, Chang, Hui, Lv, Yong-Gang, Yu, Jin-Wen, Bai, Yun-Gang, Liu, Huan, Cai, Yue, Wang, Ling, Ma, Jin, Chang, Yao-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257261/ https://www.ncbi.nlm.nih.gov/pubmed/22253932 http://dx.doi.org/10.1371/journal.pone.0030387 |
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