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NMR Derived Model of GTPase Effector Domain (GED) Self Association: Relevance to Dynamin Assembly

Self-association of dynamin to form spiral structures around lipidic vesicles during endocytosis is largely mediated by its ‘coiled coil’ GTPase Effector Domain (GED), which, in vitro, self-associates into huge helical assemblies. Residue-level structural characterizations of these assemblies and un...

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Detalles Bibliográficos
Autores principales: Chakraborty, Swagata, Pratihar, Supriya, Hosur, Ramakrishna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257262/
https://www.ncbi.nlm.nih.gov/pubmed/22253896
http://dx.doi.org/10.1371/journal.pone.0030109