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Immunological Evaluation of Lipopeptide Group A Streptococcus (GAS) Vaccine: Structure-Activity Relationship

Streptococcus pyogenes (group A streptococcus, GAS) is a Gram-positive bacterial pathogen responsible for a wide variety of diseases. To date, GAS vaccine development has focused primarily on the M-protein. The M-protein is highly variable at the amino (N)-terminus (determining serotype) but is cons...

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Detalles Bibliográficos
Autores principales: Zaman, Mehfuz, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Phillipps, Karen S. M., Batzloff, Michael R., Good, Michael F., Toth, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257266/
https://www.ncbi.nlm.nih.gov/pubmed/22253911
http://dx.doi.org/10.1371/journal.pone.0030146