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Global Analysis of Small Molecule Binding to Related Protein Targets
We report on the integration of pharmacological data and homology information for a large scale analysis of small molecule binding to related targets. Differences in small molecule binding have been assessed for curated pairs of human to rat orthologs and also for recently diverged human paralogs. O...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257267/ https://www.ncbi.nlm.nih.gov/pubmed/22253582 http://dx.doi.org/10.1371/journal.pcbi.1002333 |