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Kinetic Rate Constant Prediction Supports the Conformational Selection Mechanism of Protein Binding
The prediction of protein-protein kinetic rate constants provides a fundamental test of our understanding of molecular recognition, and will play an important role in the modeling of complex biological systems. In this paper, a feature selection and regression algorithm is applied to mine a large se...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257286/ https://www.ncbi.nlm.nih.gov/pubmed/22253587 http://dx.doi.org/10.1371/journal.pcbi.1002351 |