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Calpains Mediate Integrin Attachment Complex Maintenance of Adult Muscle in Caenorhabditis elegans

Two components of integrin containing attachment complexes, UNC-97/PINCH and UNC-112/MIG-2/Kindlin-2, were recently identified as negative regulators of muscle protein degradation and as having decreased mRNA levels in response to spaceflight. Integrin complexes transmit force between the inside and...

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Detalles Bibliográficos
Autores principales: Etheridge, Timothy, Oczypok, Elizabeth A., Lehmann, Susann, Fields, Brandon D., Shephard, Freya, Jacobson, Lewis A., Szewczyk, Nathaniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257289/
https://www.ncbi.nlm.nih.gov/pubmed/22253611
http://dx.doi.org/10.1371/journal.pgen.1002471