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Calpains Mediate Integrin Attachment Complex Maintenance of Adult Muscle in Caenorhabditis elegans
Two components of integrin containing attachment complexes, UNC-97/PINCH and UNC-112/MIG-2/Kindlin-2, were recently identified as negative regulators of muscle protein degradation and as having decreased mRNA levels in response to spaceflight. Integrin complexes transmit force between the inside and...
Autores principales: | Etheridge, Timothy, Oczypok, Elizabeth A., Lehmann, Susann, Fields, Brandon D., Shephard, Freya, Jacobson, Lewis A., Szewczyk, Nathaniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257289/ https://www.ncbi.nlm.nih.gov/pubmed/22253611 http://dx.doi.org/10.1371/journal.pgen.1002471 |
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