An siRNA Screen in Pancreatic Beta Cells Reveals a Role for Gpr27 in Insulin Production

The prevalence of type 2 diabetes in the United States is projected to double or triple by 2050. We reasoned that the genes that modulate insulin production might be new targets for diabetes therapeutics. Therefore, we developed an siRNA screening system to identify genes important for the activity...

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Detalles Bibliográficos
Autores principales: Ku, Gregory M., Pappalardo, Zachary, Luo, Chun Chieh, German, Michael S., McManus, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257298/
https://www.ncbi.nlm.nih.gov/pubmed/22253604
http://dx.doi.org/10.1371/journal.pgen.1002449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257298/
https://www.ncbi.nlm.nih.gov/pubmed/22253604
http://dx.doi.org/10.1371/journal.pgen.1002449

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