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An siRNA Screen in Pancreatic Beta Cells Reveals a Role for Gpr27 in Insulin Production
The prevalence of type 2 diabetes in the United States is projected to double or triple by 2050. We reasoned that the genes that modulate insulin production might be new targets for diabetes therapeutics. Therefore, we developed an siRNA screening system to identify genes important for the activity...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257298/ https://www.ncbi.nlm.nih.gov/pubmed/22253604 http://dx.doi.org/10.1371/journal.pgen.1002449 |