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Mechanisms of NK Cell-Macrophage Bacillus anthracis Crosstalk: A Balance between Stimulation by Spores and Differential Disruption by Toxins

NK cells are important immune effectors for preventing microbial invasion and dissemination, through natural cytotoxicity and cytokine secretion. Bacillus anthracis spores can efficiently drive IFN-γ production by NK cells. The present study provides insights into the mechanisms of cytokine and cell...

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Detalles Bibliográficos
Autores principales: Klezovich-Bénard, Maria, Corre, Jean-Philippe, Jusforgues-Saklani, Hélène, Fiole, Daniel, Burjek, Nick, Tournier, Jean-Nicolas, Goossens, Pierre L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257302/
https://www.ncbi.nlm.nih.gov/pubmed/22253596
http://dx.doi.org/10.1371/journal.ppat.1002481