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Insulin rapidly stimulates l-arginine transport in human aortic endothelial cells via Akt

Insulin stimulates endothelial NO synthesis, at least in part mediated by phosphorylation and activation of endothelial NO synthase at Ser1177 and Ser615 by Akt. We have previously demonstrated that insulin-stimulated NO synthesis is inhibited under high culture glucose conditions, without altering...

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Detalles Bibliográficos
Autores principales: Kohlhaas, Christine F., Morrow, Valerie A., Jhakra, Neelam, Patil, Vrushali, Connell, John M.C., Petrie, John R., Salt, Ian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257429/
https://www.ncbi.nlm.nih.gov/pubmed/21871446
http://dx.doi.org/10.1016/j.bbrc.2011.08.048