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Insulin rapidly stimulates l-arginine transport in human aortic endothelial cells via Akt
Insulin stimulates endothelial NO synthesis, at least in part mediated by phosphorylation and activation of endothelial NO synthase at Ser1177 and Ser615 by Akt. We have previously demonstrated that insulin-stimulated NO synthesis is inhibited under high culture glucose conditions, without altering...
Autores principales: | Kohlhaas, Christine F., Morrow, Valerie A., Jhakra, Neelam, Patil, Vrushali, Connell, John M.C., Petrie, John R., Salt, Ian P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257429/ https://www.ncbi.nlm.nih.gov/pubmed/21871446 http://dx.doi.org/10.1016/j.bbrc.2011.08.048 |
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