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Hsp42 is required for sequestration of protein aggregates into deposition sites in Saccharomyces cerevisiae

The aggregation of proteins inside cells is an organized process with cytoprotective function. In Saccharomyces cerevisiae, aggregating proteins are spatially sequestered to either juxtanuclear or peripheral sites, which target distinct quality control pathways for refolding and degradation. The cel...

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Detalles Bibliográficos
Autores principales: Specht, Sebastian, Miller, Stephanie B.M., Mogk, Axel, Bukau, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257523/
https://www.ncbi.nlm.nih.gov/pubmed/22065637
http://dx.doi.org/10.1083/jcb.201106037