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Hsp42 is required for sequestration of protein aggregates into deposition sites in Saccharomyces cerevisiae
The aggregation of proteins inside cells is an organized process with cytoprotective function. In Saccharomyces cerevisiae, aggregating proteins are spatially sequestered to either juxtanuclear or peripheral sites, which target distinct quality control pathways for refolding and degradation. The cel...
Autores principales: | Specht, Sebastian, Miller, Stephanie B.M., Mogk, Axel, Bukau, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257523/ https://www.ncbi.nlm.nih.gov/pubmed/22065637 http://dx.doi.org/10.1083/jcb.201106037 |
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