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The Rap1–Rgl–Ral signaling network regulates neuroblast cortical polarity and spindle orientation

A crucial first step in asymmetric cell division is to establish an axis of cell polarity along which the mitotic spindle aligns. Drosophila melanogaster neural stem cells, called neuroblasts (NBs), divide asymmetrically through intrinsic polarity cues, which regulate spindle orientation and cortica...

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Detalles Bibliográficos
Autores principales: Carmena, Ana, Makarova, Aljona, Speicher, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257524/
https://www.ncbi.nlm.nih.gov/pubmed/22084305
http://dx.doi.org/10.1083/jcb.201108112