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Cdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation

Cdk1 controls many aspects of mitotic chromosome behavior and spindle microtubule (MT) dynamics to ensure accurate chromosome segregation. In this paper, we characterize a new kinetochore substrate of fission yeast Cdk1, Nsk1, which promotes proper kinetochore–MT (k-MT) interactions and chromosome m...

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Detalles Bibliográficos
Autores principales: Chen, Jun-Song, Lu, Lucy X., Ohi, Melanie D., Creamer, Kevin M., English, Chauca, Partridge, Janet F., Ohi, Ryoma, Gould, Kathleen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257533/
https://www.ncbi.nlm.nih.gov/pubmed/22065639
http://dx.doi.org/10.1083/jcb.201105074