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Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

Intracellular and extracellular mechanical forces affect the structure and dynamics of the actin cytoskeleton. However, the underlying molecular and biophysical mechanisms, including how mechanical forces are sensed, are largely unknown. Actin-depolymerizing factor/cofilin proteins are actin-modulat...

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Detalles Bibliográficos
Autores principales: Hayakawa, Kimihide, Tatsumi, Hitoshi, Sokabe, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257564/
https://www.ncbi.nlm.nih.gov/pubmed/22123860
http://dx.doi.org/10.1083/jcb.201102039