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Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament
Intracellular and extracellular mechanical forces affect the structure and dynamics of the actin cytoskeleton. However, the underlying molecular and biophysical mechanisms, including how mechanical forces are sensed, are largely unknown. Actin-depolymerizing factor/cofilin proteins are actin-modulat...
Autores principales: | Hayakawa, Kimihide, Tatsumi, Hitoshi, Sokabe, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257564/ https://www.ncbi.nlm.nih.gov/pubmed/22123860 http://dx.doi.org/10.1083/jcb.201102039 |
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