Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

Invadopodia are invasive protrusions with proteolytic activity uniquely found in tumor cells. Cortactin phosphorylation is a key step during invadopodia maturation, regulating Nck1 binding and cofilin activity. The precise mechanism of cortactin-dependent cofilin regulation and the roles of this pat...

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Detalles Bibliográficos
Autores principales: Magalhaes, Marco A. O., Larson, Daniel R., Mader, Christopher C., Bravo-Cordero, Jose Javier, Gil-Henn, Hava, Oser, Matthew, Chen, Xiaoming, Koleske, Anthony J., Condeelis, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257566/
https://www.ncbi.nlm.nih.gov/pubmed/22105349
http://dx.doi.org/10.1083/jcb.201103045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257566/
https://www.ncbi.nlm.nih.gov/pubmed/22105349
http://dx.doi.org/10.1083/jcb.201103045

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