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Bestrophin1 Channels are Insensitive to Ethanol and Do not Mediate Tonic GABAergic Currents in Cerebellar Granule Cells

The granule cell layer of the cerebellum functions in spatio-temporal encoding of information. Granule cells (GCs) are tonically inhibited by spillover of GABA released from Golgi cells and this tonic inhibition is facilitated by acute ethanol. Recently, it was demonstrated that a specialized Ca(2+)...

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Detalles Bibliográficos
Autores principales: Diaz, Marvin R., Wadleigh, Aya, Hughes, Benjamin A., Woodward, John J., Valenzuela, C. Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257865/
https://www.ncbi.nlm.nih.gov/pubmed/22275879
http://dx.doi.org/10.3389/fnins.2011.00148