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Inhibition of the Plasma-Membrane-Associated Serine Protease Cathepsin G by Mycobacterium tuberculosis Rv3364c Suppresses Caspase-1 and Pyroptosis in Macrophages

Tuberculosis is a disease associated with the infection of a great part of the world’s population and is responsible for the death of two to three million people annually. Mycobacterium tuberculosis infects macrophages and subverts its mechanisms of killing. The pathogen suppresses macrophage apopto...

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Detalles Bibliográficos
Autores principales: Danelishvili, Lia, Everman, Jamie L., McNamara, Michael J., Bermudez, Luiz E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257866/
https://www.ncbi.nlm.nih.gov/pubmed/22275911
http://dx.doi.org/10.3389/fmicb.2011.00281