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Son maintains accurate splicing for a subset of human pre-mRNAs

Serine-arginine-rich (SR) proteins play a key role in alternative pre-mRNA splicing in eukaryotes. We recently showed that a large SR protein called Son has unique repeat motifs that are essential for maintaining the subnuclear organization of pre-mRNA processing factors in nuclear speckles. Motif a...

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Detalles Bibliográficos
Autores principales: Sharma, Alok, Markey, Michael, Torres-Muñoz, Keshia, Varia, Sapna, Kadakia, Madhavi, Bubulya, Athanasios, Bubulya, Paula A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258111/
https://www.ncbi.nlm.nih.gov/pubmed/22193954
http://dx.doi.org/10.1242/jcs.092239