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IRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress

Physiological and pathophysiological stress attenuates global translation via phosphorylation of eIF2α. This in turn leads to the reprogramming of gene expression that is required for adaptive stress response. One class of cellular messenger RNAs whose translation was reported to be insensitive to e...

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Detalles Bibliográficos
Autores principales: Thakor, Nehal, Holcik, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258125/
https://www.ncbi.nlm.nih.gov/pubmed/21917851
http://dx.doi.org/10.1093/nar/gkr701